Biologic Drugs for the Treatment of Noninfectious Uveitis

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منابع مشابه

[New drugs in the treatment of noninfectious uveitis].

Uveitis is considered to cause approximately 10% of blindness in the USA. This underlies the need for new treatments for some noninfectious uveitis, as the success rate of conventional immunosuppressant treatments is low and involve important side effects. Accordingly, it is necessary to research with new drugs having a more selective action mechanism with more potency for controlling long-term...

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Voclosporin is a relatively new calcineurin inhibitor that has been used successfully in humans for the treatment of plaque psoriasis. Available data indicate a good safety profile for this treatment and a significant increase in quality of life for psoriasis patients. More recently, voclosporin has been used to treat ophthalmic conditions such as uveitis. The limited data available indicate at...

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A review and update on orphan drugs for the treatment of noninfectious uveitis

INTRODUCTION Uveitis, a leading cause of preventable blindness around the world, is a critically underserved disease in regard to the medications approved for use. Multiple immunomodulatory therapy (IMT) drugs are appropriate for uveitis therapy but are still off-label. These IMT agents, including antimetabolites, calcineurin inhibitors, alkylating agents, and biologic agents, have been designa...

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Uveitis can be a sight-threatening eye disease with significant morbidity. Corticosteroids remain the mainstay of treatment of uveitis and provide an effective treatment against ocular inflammation. However, the various modes available for corticosteroid drug delivery can carry significant ocular and systemic side effects which can limit their use in the treatment of uveitis. In an effort to av...

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ژورنال

عنوان ژورنال: Asia-Pacific Journal of Ophthalmology

سال: 2021

ISSN: 2162-0989

DOI: 10.1097/apo.0000000000000371